Unique stable helper virus-free AAV production system, addressing the production gap in AAV-based gene therapies.

AAV manufacturing using stable cell lines is the best option for scaling up the production process. Stable AAV producer cell lines avoid the challenges of transient transfections.

Screening of 2 different batches of single cell clones of the stable AAV packaging platform identifies clones with comparable productivity to the transient approach, even before process optimization.